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www.leibniz-fli.de |
The Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena is a federal and state government-funded research institute and member of the Leibniz Association (Leibniz-Gemeinschaft). FLI’ s internationally visible and highly competitive research is focused on understanding the mechanisms of aging and associated age-related diseases. Scientists from over 40 countries are currently investigating the molecular mechanisms of aging and the occurrence of age-related diseases. Our aim is to create the basis for new approaches in medicine as a way to improve the health of the elderly (www.leibniz-fli.de).
The Research group of Dr. Maria Ermolaeva is seeking Postdoctoral Researchers (m/f/x) to join the ERC funded research project LifeLongFit.
Tasks and Challenges:The LifeLongFit ERC project aims to find effective ways to extend lifespan at different ages. It builds on the discovery that metformin's benefits for longevity diminish in old organisms due to a loss of metabolic flexibility. This suggests that interventions developed in young organisms may not work well later in life. The project will explore age limitations of longevity treatments that rely on cellular resilience responses, like microbiome interventions and moderate stress inducers. Focusing on the specific intervention type, each Postdoc will use various techniques in C.elegans and human cells (i.e. Omics, genetics, drug screens) to (a) understand why age-related limitations occur and (b) restore youthful responses in older organisms. Finally, in vivo studies in vertebrates will be initiated to validate the newly developed longevitiy strategies. |
Requirements:
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Please apply online through the FLI application portal by 30.11.2023.
Applications will be analyzed regarding skills, competences and qualifications. All qualified persons, regardless of gender, nationality, ethnic and social origin, religion or belief, disability, age, sexual orientation and identity or other classification protected by law will receive consideration for employment.
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